Scientists isolate new antibodies to fight human respiratory syncytial virus (RSV) - 13 February 2017
Researchers from VIB, UGent, the Geisel School of Medicine at Dartmouth and several collaborators developed a new antiviral strategy to fight human respiratory syncytial virus (RSV), a leading cause of lower respiratory tract infections in children. The approach hinges on the use of single-domain antibodies, also known as Nanobodies®, which target and neutralize a vital protein in the virus, rendering it unable to enter lung cells. The research, published in the leading scientific journal Nature Communications, elucidates how these Nanobodies® interact with and neutralize the virus and demonstrates their ability to successfully protect mice from RSV infection and related inflammation.
Diverse VIB team investigates the possibilities of plant proteins - 11 February 2017
Although both plants and animals are made up of cells, plants are generally unable to relocate, and thus can’t migrate around freely like animals can. These constraints lead them to grow through cell division in three directions – forward, sideways or upwards – with proteins playing a role in giving cells the “identities” that eventually lead to wood and other plant tissues. A multidisciplinary group of scientists from the VIB-UGent Center for Plant Systems Biology and the VIB-UGent Center for Medical Biotechnology recently collaborated on fundamental research that explores how the processes of plant root growth and patterning are affected by proteins – specifically, those that interact with a protein called ACR4.
Talking protein tags, novel ideas and tech innovation - 5 November 2016
As one of our Expert Scientists, Sven Eyckerman knows all about the ‘tech’ in ‘biotechnology’.
Together with his VIB-Ghent University research team, he has been working on several innovative biotechnologies. A recent example is the generic Virotrap platform, as seen in VIBnews June. Shortly after, Sven and his team came up with yet another pioneering technique. They developed a set of universal protein tags that go by the acronym of ‘PQS’ and enable protein quantification via targeted proteomic techniques. Sven talks you through the how and why of this new tool and tech innovation in general.
Immunovaccine Announces Positive Phase 1 Topline Data for DepoVax™-based Respiratory Syncytial Virus Vaccine Candidate - 13 October 2016
Immunovaccine Inc. (“Immunovaccine” or the “Company”) (TSX: IMV; OTCQX: IMMVF), a clinical stage vaccine and immunotherapy company, today announced positive topline results from its Phase 1 trial evaluating the safety and immunogenicity of DPX-RSV, its DepoVax™-based, small B cell epitope peptide vaccine candidate for respiratory syncytial virus (RSV). The results six months or more after vaccination confirmed earlier-reported interim data on the ability of DepoVax™- formulated antigens to generate a relevant, durable immune response.